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Microfluidic converging/diverging channels optimised for homogeneous extensional deformation

In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspe...

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Autores principales: Zografos, K., Pimenta, F., Alves, M. A., Oliveira, M. S. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947041/
https://www.ncbi.nlm.nih.gov/pubmed/27478523
http://dx.doi.org/10.1063/1.4954814
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author Zografos, K.
Pimenta, F.
Alves, M. A.
Oliveira, M. S. N.
author_facet Zografos, K.
Pimenta, F.
Alves, M. A.
Oliveira, M. S. N.
author_sort Zografos, K.
collection PubMed
description In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspect ratio and dimensionless contraction length are investigated. Initially, pressure driven flows of Newtonian fluids under creeping flow conditions are considered, which is a reasonable approximation in microfluidics, and the limits of the applicability of the design in terms of Reynolds numbers are investigated. The optimised geometry is then used for studying the flow of viscoelastic fluids and the practical limitations in terms of Weissenberg number are reported. Furthermore, the optimisation strategy is also applied for electro-osmotic driven flows, where the development of a plug-like velocity profile allows for a wider region of homogeneous extensional deformation in the flow field.
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spelling pubmed-49470412016-07-29 Microfluidic converging/diverging channels optimised for homogeneous extensional deformation Zografos, K. Pimenta, F. Alves, M. A. Oliveira, M. S. N. Biomicrofluidics SPECIAL TOPIC: INVITED ARTICLES ON MICROFLUIDIC RHEOLOGY (GUEST EDITORS ANKE LINDNER AND PAULO ARRATIA) In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspect ratio and dimensionless contraction length are investigated. Initially, pressure driven flows of Newtonian fluids under creeping flow conditions are considered, which is a reasonable approximation in microfluidics, and the limits of the applicability of the design in terms of Reynolds numbers are investigated. The optimised geometry is then used for studying the flow of viscoelastic fluids and the practical limitations in terms of Weissenberg number are reported. Furthermore, the optimisation strategy is also applied for electro-osmotic driven flows, where the development of a plug-like velocity profile allows for a wider region of homogeneous extensional deformation in the flow field. AIP Publishing LLC 2016-07-05 /pmc/articles/PMC4947041/ /pubmed/27478523 http://dx.doi.org/10.1063/1.4954814 Text en © 2016 Author(s). 1932-1058/2016/10(4)/043508/20 All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle SPECIAL TOPIC: INVITED ARTICLES ON MICROFLUIDIC RHEOLOGY (GUEST EDITORS ANKE LINDNER AND PAULO ARRATIA)
Zografos, K.
Pimenta, F.
Alves, M. A.
Oliveira, M. S. N.
Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
title Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
title_full Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
title_fullStr Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
title_full_unstemmed Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
title_short Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
title_sort microfluidic converging/diverging channels optimised for homogeneous extensional deformation
topic SPECIAL TOPIC: INVITED ARTICLES ON MICROFLUIDIC RHEOLOGY (GUEST EDITORS ANKE LINDNER AND PAULO ARRATIA)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947041/
https://www.ncbi.nlm.nih.gov/pubmed/27478523
http://dx.doi.org/10.1063/1.4954814
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