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Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947041/ https://www.ncbi.nlm.nih.gov/pubmed/27478523 http://dx.doi.org/10.1063/1.4954814 |
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author | Zografos, K. Pimenta, F. Alves, M. A. Oliveira, M. S. N. |
author_facet | Zografos, K. Pimenta, F. Alves, M. A. Oliveira, M. S. N. |
author_sort | Zografos, K. |
collection | PubMed |
description | In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspect ratio and dimensionless contraction length are investigated. Initially, pressure driven flows of Newtonian fluids under creeping flow conditions are considered, which is a reasonable approximation in microfluidics, and the limits of the applicability of the design in terms of Reynolds numbers are investigated. The optimised geometry is then used for studying the flow of viscoelastic fluids and the practical limitations in terms of Weissenberg number are reported. Furthermore, the optimisation strategy is also applied for electro-osmotic driven flows, where the development of a plug-like velocity profile allows for a wider region of homogeneous extensional deformation in the flow field. |
format | Online Article Text |
id | pubmed-4947041 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-49470412016-07-29 Microfluidic converging/diverging channels optimised for homogeneous extensional deformation Zografos, K. Pimenta, F. Alves, M. A. Oliveira, M. S. N. Biomicrofluidics SPECIAL TOPIC: INVITED ARTICLES ON MICROFLUIDIC RHEOLOGY (GUEST EDITORS ANKE LINDNER AND PAULO ARRATIA) In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspect ratio and dimensionless contraction length are investigated. Initially, pressure driven flows of Newtonian fluids under creeping flow conditions are considered, which is a reasonable approximation in microfluidics, and the limits of the applicability of the design in terms of Reynolds numbers are investigated. The optimised geometry is then used for studying the flow of viscoelastic fluids and the practical limitations in terms of Weissenberg number are reported. Furthermore, the optimisation strategy is also applied for electro-osmotic driven flows, where the development of a plug-like velocity profile allows for a wider region of homogeneous extensional deformation in the flow field. AIP Publishing LLC 2016-07-05 /pmc/articles/PMC4947041/ /pubmed/27478523 http://dx.doi.org/10.1063/1.4954814 Text en © 2016 Author(s). 1932-1058/2016/10(4)/043508/20 All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | SPECIAL TOPIC: INVITED ARTICLES ON MICROFLUIDIC RHEOLOGY (GUEST EDITORS ANKE LINDNER AND PAULO ARRATIA) Zografos, K. Pimenta, F. Alves, M. A. Oliveira, M. S. N. Microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
title | Microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
title_full | Microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
title_fullStr | Microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
title_full_unstemmed | Microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
title_short | Microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
title_sort | microfluidic converging/diverging channels optimised for homogeneous extensional deformation |
topic | SPECIAL TOPIC: INVITED ARTICLES ON MICROFLUIDIC RHEOLOGY (GUEST EDITORS ANKE LINDNER AND PAULO ARRATIA) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947041/ https://www.ncbi.nlm.nih.gov/pubmed/27478523 http://dx.doi.org/10.1063/1.4954814 |
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