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Fluorescence imaging of ATP in neutrophils from patients with sepsis using organelle-localizable fluorescent chemosensors
BACKGROUND: The activation of polymorphonuclear neutrophils (PMNs) plays an important role in sepsis. Previously, we showed that ATP release and feedback via ATP receptors are essential for PMN activation; however, the dynamics remain poorly understood. Two new fluorescent chemosensors, PMAP-1 and M...
Autores principales: | Sueyoshi, Koichiro, Sumi, Yuka, Inoue, Yoshiaki, Kuroda, Yoko, Ishii, Kumiko, Nakayama, Hitoshi, Iwabuchi, Kazuhisa, Kurishita, Yasutaka, Shigemitsu, Hajime, Hamachi, Itaru, Tanaka, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Paris
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947066/ https://www.ncbi.nlm.nih.gov/pubmed/27422255 http://dx.doi.org/10.1186/s13613-016-0175-z |
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