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Classification of different Hepatitis B infected individuals with saturated incidence rate

The role of incidence rate is very important in the study of epidemiological models. In this article, the analysis of an epidemic problem for the transmission dynamic of HBV with saturated incidence rate is presented, which is more generalize than bilinear incidence rate. After formulating the new m...

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Detalles Bibliográficos
Autores principales: Khan, Tahir, Zaman, Gul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947085/
https://www.ncbi.nlm.nih.gov/pubmed/27468382
http://dx.doi.org/10.1186/s40064-016-2706-3
Descripción
Sumario:The role of incidence rate is very important in the study of epidemiological models. In this article, the analysis of an epidemic problem for the transmission dynamic of HBV with saturated incidence rate is presented, which is more generalize than bilinear incidence rate. After formulating the new mathematical model, the threshold quantity reproduction number [Formula: see text] is investigated by using the well known approach i.e. next generation matrix and investigate the possible equilibriums such as disease free and endemic equilibria. Then for the local and global behavior of the proposed problem, the local asymptotic stability analysis as well as global asymptotic stability analysis are proved. To prove the global asymptotic stability at disease free equilibrium, the classic Lyapunov function theory is considered. Similarly to show global asymptotic stability at endemic equilibria, the geometrical approach is used, which is the generalization of Lyapunov theory. Finally, numeric of the proposed problem are carried out to show the feasibility of the obtained results and the role of saturated incidence rate.