Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease with no effective treatment available. An increasing number of genetic causes of ALS are being identified, but how these genetic defects lead to motor neuron degeneration and to which extent they affect common cellular pathway...

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Detalles Bibliográficos
Autores principales: Blokhuis, Anna M., Koppers, Max, Groen, Ewout J. N., van den Heuvel, Dianne M. A., Dini Modigliani, Stefano, Anink, Jasper J., Fumoto, Katsumi, van Diggelen, Femke, Snelting, Anne, Sodaar, Peter, Verheijen, Bert M., Demmers, Jeroen A. A., Veldink, Jan H., Aronica, Eleonora, Bozzoni, Irene, den Hertog, Jeroen, van den Berg, Leonard H., Pasterkamp, R. Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947123/
https://www.ncbi.nlm.nih.gov/pubmed/27164932
http://dx.doi.org/10.1007/s00401-016-1575-8

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