The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2

The Fanconi anaemia (FA) pathway is important for the repair of DNA interstrand crosslinks (ICL). The FANCD2–FANCI complex is central to the pathway, and localizes to ICLs dependent on its monoubiquitination. It has remained elusive whether the complex is recruited before or after the critical monou...

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Detalles Bibliográficos
Autores principales: Liang, Chih-Chao, Li, Zhuolun, Lopez-Martinez, David, Nicholson, William V., Vénien-Bryan, Catherine, Cohn, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947157/
https://www.ncbi.nlm.nih.gov/pubmed/27405460
http://dx.doi.org/10.1038/ncomms12124

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