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RNA polymerase I–Rrn3 complex at 4.8 Å resolution

Transcription of ribosomal DNA by RNA polymerase I (Pol I) requires the initiation factor Rrn3. Here we report the cryo-EM structure of the Pol I–Rrn3 complex at 4.8 Å resolution. The structure reveals how Rrn3 binding converts an inactive Pol I dimer into an initiation-competent monomeric complex a...

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Detalles Bibliográficos
Autores principales:	Engel, Christoph, Plitzko, Jürgen, Cramer, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947163/ https://www.ncbi.nlm.nih.gov/pubmed/27418309 http://dx.doi.org/10.1038/ncomms12129

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