Brain region-specific effects of cGMP-dependent kinase II knockout on AMPA receptor trafficking and animal behavior

Phosphorylation of GluA1, a subunit of AMPA receptors (AMPARs), is critical for AMPAR synaptic trafficking and control of synaptic transmission. cGMP-dependent protein kinase II (cGKII) mediates this phosphorylation, and cGKII knockout (KO) affects GluA1 phosphorylation and alters animal behavior. N...

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Detalles Bibliográficos
Autores principales: Kim, Seonil, Pick, Joseph E., Abera, Sinedu, Khatri, Latika, Ferreira, Danielle D.P., Sathler, Matheus F., Morison, Sage L., Hofmann, Franz, Ziff, Edward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947234/
https://www.ncbi.nlm.nih.gov/pubmed/27421896
http://dx.doi.org/10.1101/lm.042960.116

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