Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine

BACKGROUND: Patients with clear cell renal cell carcinoma (ccRCC) have few therapeutic options, as ccRCC is unresponsive to chemotherapy and is highly resistant to radiation. Recently targeted therapies have extended progression-free survival, but responses are variable and no significant overall su...

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Detalles Bibliográficos
Autores principales: Lobo, Nazleen C., Gedye, Craig, Apostoli, Anthony J., Brown, Kevin R., Paterson, Joshua, Stickle, Natalie, Robinette, Michael, Fleshner, Neil, Hamilton, Robert J., Kulkarni, Girish, Zlotta, Alexandre, Evans, Andrew, Finelli, Antonio, Moffat, Jason, Jewett, Michael A. S., Ailles, Laurie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947293/
https://www.ncbi.nlm.nih.gov/pubmed/27422173
http://dx.doi.org/10.1186/s12885-016-2539-z

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