Osteopontin and thrombospondin-1 play opposite roles in promoting tumor aggressiveness of primary resected non-small cell lung cancer

BACKGROUND: Osteopontin (OPN) and thrombospondin-1 (TSP-1) are extracellular matrix proteins secreted by stromal and tumor cells. These proteins appear to have a key role in the tumor microenvironment for cancer development and metastasis. There is little information regarding the prognostic value o...

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Detalles Bibliográficos
Autores principales: Rouanne, Mathieu, Adam, Julien, Goubar, Aïcha, Robin, Angélique, Ohana, Caroline, Louvet, Emilie, Cormier, Jiemin, Mercier, Olaf, Dorfmüller, Peter, Fattal, Soly, de Montpreville, Vincent Thomas, Lebret, Thierry, Dartevelle, Philippe, Fadel, Elie, Besse, Benjamin, Olaussen, Ken André, Auclair, Christian, Soria, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947364/
https://www.ncbi.nlm.nih.gov/pubmed/27422280
http://dx.doi.org/10.1186/s12885-016-2541-5

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