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Adverse prognostic impact of the CpG island methylator phenotype in metastatic colorectal cancer

BACKGROUND: The association between the CpG island methylator phenotype (CIMP) and clinical outcomes in metastatic colorectal cancer remains unclear. We investigated the prognostic impact of CIMP in patients with metastatic colorectal cancer treated with systemic chemotherapy. METHODS: Eight CIMP-sp...

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Detalles Bibliográficos
Autores principales: Cha, Yongjun, Kim, Kyung-Ju, Han, Sae-Won, Rhee, Ye Young, Bae, Jeong Mo, Wen, Xianyu, Cho, Nam-Yun, Lee, Dae-Won, Lee, Kyung-Hun, Kim, Tae-Yong, Oh, Do-Youn, Im, Seock-Ah, Bang, Yung-Jue, Jeong, Seung-Yong, Park, Kyu Joo, Kang, Gyeong Hoon, Kim, Tae-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947699/
https://www.ncbi.nlm.nih.gov/pubmed/27310704
http://dx.doi.org/10.1038/bjc.2016.176

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