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Overexpression of the oncostatin-M receptor in cervical squamous cell carcinoma is associated with epithelial–mesenchymal transition and poor overall survival
BACKGROUND: Copy-number gain of the oncostatin-M receptor (OSMR) occurs frequently in cervical squamous cell carcinoma (SCC) and is associated with adverse clinical outcome. We previously showed that OSMR overexpression renders cervical SCC cells more sensitive to the major ligand oncostatin-M (OSM)...
Autores principales: | Kucia-Tran, Justyna A, Tulkki, Valtteri, Smith, Stephen, Scarpini, Cinzia G, Hughes, Katherine, Araujo, Angela M, Yan, Ka Yin Matthew, Botthof, Jan, Pérez-Gómez, Eduardo, Quintanilla, Miguel, Cuschieri, Kate, Caffarel, Maria M, Coleman, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947707/ https://www.ncbi.nlm.nih.gov/pubmed/27351213 http://dx.doi.org/10.1038/bjc.2016.199 |
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