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Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo

The regulated differentiation of macrophages (mφs) and their subsequent activation into proinflammatory or prohealing subtypes is critical for efficient wound healing. Chronic wounds such as diabetic (db) ulcers are associated with dysregulation of macrophage function. Whereas non-db mφs polarize to...

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Detalles Bibliográficos
Autores principales: Al Sadoun, Hadeel, Burgess, Matthew, Hentges, Kathryn E., Mace, Kimberly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947829/
https://www.ncbi.nlm.nih.gov/pubmed/27342843
http://dx.doi.org/10.4049/jimmunol.1501944

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