Annexin A1 translocates to nucleus and promotes the expression of pro-inflammatory cytokines in a PKC-dependent manner after OGD/R

Annexin A1 (ANXA1) is a protein known to have multiple roles in the regulation of inflammatory responses. In this study, we find that after oxygen glucose deprivation/reoxygenation (ODG/R) injury, activated PKC phosphorylated ANXA1 at the serine 27 residue (p27S-ANXA1), and promoted the translocatio...

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Detalles Bibliográficos
Autores principales: Zhao, Baoming, Wang, Jing, Liu, Lu, Li, Xing, Liu, Shuangxi, Xia, Qian, Shi, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947919/
https://www.ncbi.nlm.nih.gov/pubmed/27426034
http://dx.doi.org/10.1038/srep27028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947919/
https://www.ncbi.nlm.nih.gov/pubmed/27426034
http://dx.doi.org/10.1038/srep27028

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