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Modeling of the Binding of Peptide Blockers to Voltage-Gated Potassium Channels: Approaches and Evidence

Modeling of the structure of voltage-gated potassium (KV) channels bound to peptide blockers aims to identify the key amino acid residues dictating affinity and provide insights into the toxin-channel interface. Computational approaches open up possibilities for in silico rational design of selectiv...

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Detalles Bibliográficos
Autores principales: Novoseletsky, V. N., Volyntseva, A. D., Shaitan, K. V., Kirpichnikov, M. P., Feofanov, A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947987/
https://www.ncbi.nlm.nih.gov/pubmed/27437138

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