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Modeling of the Binding of Peptide Blockers to Voltage-Gated Potassium Channels: Approaches and Evidence
Modeling of the structure of voltage-gated potassium (KV) channels bound to peptide blockers aims to identify the key amino acid residues dictating affinity and provide insights into the toxin-channel interface. Computational approaches open up possibilities for in silico rational design of selectiv...
Autores principales: | Novoseletsky, V. N., Volyntseva, A. D., Shaitan, K. V., Kirpichnikov, M. P., Feofanov, A. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947987/ https://www.ncbi.nlm.nih.gov/pubmed/27437138 |
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