Heat Stress-Induced DNA Damage

Although the heat-stress response has been extensively studied for decades, very little is known about its effects on nucleic acids and nucleic acid-associated processes. This is due to the fact that the research has focused on the study of heat shock proteins and factors (HSPs and HSFs), their invo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kantidze, O.L., Velichko, A.K., Luzhin, A.V., Razin, S.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947990/
https://www.ncbi.nlm.nih.gov/pubmed/27437141
_version_ 1782443265184759808
author Kantidze, O.L.
Velichko, A.K.
Luzhin, A.V.
Razin, S.V.
author_facet Kantidze, O.L.
Velichko, A.K.
Luzhin, A.V.
Razin, S.V.
author_sort Kantidze, O.L.
collection PubMed
description Although the heat-stress response has been extensively studied for decades, very little is known about its effects on nucleic acids and nucleic acid-associated processes. This is due to the fact that the research has focused on the study of heat shock proteins and factors (HSPs and HSFs), their involvement in the regulation of transcription, protein homeostasis, etc. Recently, there has been some progress in the study of heat stress effects on DNA integrity. In this review, we summarize and discuss well-known and potential mechanisms of formation of various heat stress-induced DNA damage.
format Online
Article
Text
id pubmed-4947990
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher A.I. Gordeyev
record_format MEDLINE/PubMed
spelling pubmed-49479902016-07-19 Heat Stress-Induced DNA Damage Kantidze, O.L. Velichko, A.K. Luzhin, A.V. Razin, S.V. Acta Naturae Research Article Although the heat-stress response has been extensively studied for decades, very little is known about its effects on nucleic acids and nucleic acid-associated processes. This is due to the fact that the research has focused on the study of heat shock proteins and factors (HSPs and HSFs), their involvement in the regulation of transcription, protein homeostasis, etc. Recently, there has been some progress in the study of heat stress effects on DNA integrity. In this review, we summarize and discuss well-known and potential mechanisms of formation of various heat stress-induced DNA damage. A.I. Gordeyev 2016 /pmc/articles/PMC4947990/ /pubmed/27437141 Text en Copyright ® 2016 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kantidze, O.L.
Velichko, A.K.
Luzhin, A.V.
Razin, S.V.
Heat Stress-Induced DNA Damage
title Heat Stress-Induced DNA Damage
title_full Heat Stress-Induced DNA Damage
title_fullStr Heat Stress-Induced DNA Damage
title_full_unstemmed Heat Stress-Induced DNA Damage
title_short Heat Stress-Induced DNA Damage
title_sort heat stress-induced dna damage
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947990/
https://www.ncbi.nlm.nih.gov/pubmed/27437141
work_keys_str_mv AT kantidzeol heatstressinduceddnadamage
AT velichkoak heatstressinduceddnadamage
AT luzhinav heatstressinduceddnadamage
AT razinsv heatstressinduceddnadamage

Ejemplares similares