Cargando…

Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection

We describe a middle aged previoulsy healthy female patient who presented with clinical features suggestive of acute heart failure. Investigations revealed very high NT pro-BNP, right heart enlargement, bilateral pulmonary alveolar edema and bilateral pleural effusion. In view of falling platelet co...

Descripción completa

Detalles Bibliográficos
Autores principales: Ray, Animesh, Nangia, Vivek, Chatterji, RS, Dalal, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948236/
https://www.ncbi.nlm.nih.gov/pubmed/27578941
http://dx.doi.org/10.4103/0970-2113.184923
_version_ 1782443298682568704
author Ray, Animesh
Nangia, Vivek
Chatterji, RS
Dalal, Navin
author_facet Ray, Animesh
Nangia, Vivek
Chatterji, RS
Dalal, Navin
author_sort Ray, Animesh
collection PubMed
description We describe a middle aged previoulsy healthy female patient who presented with clinical features suggestive of acute heart failure. Investigations revealed very high NT pro-BNP, right heart enlargement, bilateral pulmonary alveolar edema and bilateral pleural effusion. In view of falling platelet counts and exudative pleural effusion inflammatory/infective causes were considered. Her Weil Felix test was strongly positive and IgM for scrub typhus also returned positive. She was started on doxycycline to which there was dramatic improvement. Thus in this case scrub typhus infection presented as acute right heart failure and the cause seemed elusive at the outset. We also systematically reviewed the existing literature on cardio-pulmonary manifestations of scrub typhus infection.
format Online
Article
Text
id pubmed-4948236
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-49482362016-08-30 Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection Ray, Animesh Nangia, Vivek Chatterji, RS Dalal, Navin Lung India Case Report We describe a middle aged previoulsy healthy female patient who presented with clinical features suggestive of acute heart failure. Investigations revealed very high NT pro-BNP, right heart enlargement, bilateral pulmonary alveolar edema and bilateral pleural effusion. In view of falling platelet counts and exudative pleural effusion inflammatory/infective causes were considered. Her Weil Felix test was strongly positive and IgM for scrub typhus also returned positive. She was started on doxycycline to which there was dramatic improvement. Thus in this case scrub typhus infection presented as acute right heart failure and the cause seemed elusive at the outset. We also systematically reviewed the existing literature on cardio-pulmonary manifestations of scrub typhus infection. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4948236/ /pubmed/27578941 http://dx.doi.org/10.4103/0970-2113.184923 Text en Copyright: © Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ray, Animesh
Nangia, Vivek
Chatterji, RS
Dalal, Navin
Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
title Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
title_full Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
title_fullStr Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
title_full_unstemmed Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
title_short Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
title_sort scrub typhus infection presenting as acute heart failure: a case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948236/
https://www.ncbi.nlm.nih.gov/pubmed/27578941
http://dx.doi.org/10.4103/0970-2113.184923
work_keys_str_mv AT rayanimesh scrubtyphusinfectionpresentingasacuteheartfailureacasereportandsystematicreviewofliteratureofcardiopulmonaryinvolvementinscrubtyphusinfection
AT nangiavivek scrubtyphusinfectionpresentingasacuteheartfailureacasereportandsystematicreviewofliteratureofcardiopulmonaryinvolvementinscrubtyphusinfection
AT chatterjirs scrubtyphusinfectionpresentingasacuteheartfailureacasereportandsystematicreviewofliteratureofcardiopulmonaryinvolvementinscrubtyphusinfection
AT dalalnavin scrubtyphusinfectionpresentingasacuteheartfailureacasereportandsystematicreviewofliteratureofcardiopulmonaryinvolvementinscrubtyphusinfection