Frequency domain photoacoustic and fluorescence microscopy

We report on simultaneous frequency domain optical-resolution photoacoustic and fluorescence microscopy with sub-µm lateral resolution. With the help of a blood smear, we show that photoacoustic and fluorescence images provide complementary information. Furthermore, we compare theoretically predicte...

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Detalles Bibliográficos
Autores principales: Langer, Gregor, Buchegger, Bianca, Jacak, Jaroslaw, Klar, Thomas A., Berer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948622/
https://www.ncbi.nlm.nih.gov/pubmed/27446698
http://dx.doi.org/10.1364/BOE.7.002692
Descripción
Sumario:We report on simultaneous frequency domain optical-resolution photoacoustic and fluorescence microscopy with sub-µm lateral resolution. With the help of a blood smear, we show that photoacoustic and fluorescence images provide complementary information. Furthermore, we compare theoretically predicted signal-to-noise ratios of sinusoidal modulation in frequency domain with pulsed excitation in time domain.

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