Frequency domain photoacoustic and fluorescence microscopy

We report on simultaneous frequency domain optical-resolution photoacoustic and fluorescence microscopy with sub-µm lateral resolution. With the help of a blood smear, we show that photoacoustic and fluorescence images provide complementary information. Furthermore, we compare theoretically predicte...

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Detalles Bibliográficos
Autores principales: Langer, Gregor, Buchegger, Bianca, Jacak, Jaroslaw, Klar, Thomas A., Berer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948622/
https://www.ncbi.nlm.nih.gov/pubmed/27446698
http://dx.doi.org/10.1364/BOE.7.002692
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author Langer, Gregor
Buchegger, Bianca
Jacak, Jaroslaw
Klar, Thomas A.
Berer, Thomas
author_facet Langer, Gregor
Buchegger, Bianca
Jacak, Jaroslaw
Klar, Thomas A.
Berer, Thomas
author_sort Langer, Gregor
collection PubMed
description We report on simultaneous frequency domain optical-resolution photoacoustic and fluorescence microscopy with sub-µm lateral resolution. With the help of a blood smear, we show that photoacoustic and fluorescence images provide complementary information. Furthermore, we compare theoretically predicted signal-to-noise ratios of sinusoidal modulation in frequency domain with pulsed excitation in time domain.
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spelling pubmed-49486222016-07-21 Frequency domain photoacoustic and fluorescence microscopy Langer, Gregor Buchegger, Bianca Jacak, Jaroslaw Klar, Thomas A. Berer, Thomas Biomed Opt Express Article We report on simultaneous frequency domain optical-resolution photoacoustic and fluorescence microscopy with sub-µm lateral resolution. With the help of a blood smear, we show that photoacoustic and fluorescence images provide complementary information. Furthermore, we compare theoretically predicted signal-to-noise ratios of sinusoidal modulation in frequency domain with pulsed excitation in time domain. Optical Society of America 2016-06-20 /pmc/articles/PMC4948622/ /pubmed/27446698 http://dx.doi.org/10.1364/BOE.7.002692 Text en Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.
spellingShingle Article
Langer, Gregor
Buchegger, Bianca
Jacak, Jaroslaw
Klar, Thomas A.
Berer, Thomas
Frequency domain photoacoustic and fluorescence microscopy
title Frequency domain photoacoustic and fluorescence microscopy
title_full Frequency domain photoacoustic and fluorescence microscopy
title_fullStr Frequency domain photoacoustic and fluorescence microscopy
title_full_unstemmed Frequency domain photoacoustic and fluorescence microscopy
title_short Frequency domain photoacoustic and fluorescence microscopy
title_sort frequency domain photoacoustic and fluorescence microscopy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948622/
https://www.ncbi.nlm.nih.gov/pubmed/27446698
http://dx.doi.org/10.1364/BOE.7.002692
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AT klarthomasa frequencydomainphotoacousticandfluorescencemicroscopy
AT bererthomas frequencydomainphotoacousticandfluorescencemicroscopy

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