Subverting lysosomal function in Trypanosoma brucei

In this issue of Microbial Cell, Koh and colleagues present data highlighting the utility of the lysosomotropic compound L-leucyl-L-leucyl methyl ester (LeuLeu-OMe) as an anti-Trypanosoma brucei agent, adding to the range of compounds that either directly target lysosomal enzymes or that can be used...

Descripción completa

Detalles Bibliográficos
Autor principal: Alsford, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948668/
https://www.ncbi.nlm.nih.gov/pubmed/27441200
http://dx.doi.org/10.15698/mic2015.08.222
_version_ 1782443310334345216
author Alsford, Sam
author_facet Alsford, Sam
author_sort Alsford, Sam
collection PubMed
description In this issue of Microbial Cell, Koh and colleagues present data highlighting the utility of the lysosomotropic compound L-leucyl-L-leucyl methyl ester (LeuLeu-OMe) as an anti-Trypanosoma brucei agent, adding to the range of compounds that either directly target lysosomal enzymes or that can be used to subvert the function of the lysosome for parasite destruction.
format Online
Article
Text
id pubmed-4948668
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Shared Science Publishers OG
record_format MEDLINE/PubMed
spelling pubmed-49486682016-07-18 Subverting lysosomal function in Trypanosoma brucei Alsford, Sam Microb Cell Microbiology In this issue of Microbial Cell, Koh and colleagues present data highlighting the utility of the lysosomotropic compound L-leucyl-L-leucyl methyl ester (LeuLeu-OMe) as an anti-Trypanosoma brucei agent, adding to the range of compounds that either directly target lysosomal enzymes or that can be used to subvert the function of the lysosome for parasite destruction. Shared Science Publishers OG 2015-08-03 /pmc/articles/PMC4948668/ /pubmed/27441200 http://dx.doi.org/10.15698/mic2015.08.222 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.
spellingShingle Microbiology
Alsford, Sam
Subverting lysosomal function in Trypanosoma brucei
title Subverting lysosomal function in Trypanosoma brucei
title_full Subverting lysosomal function in Trypanosoma brucei
title_fullStr Subverting lysosomal function in Trypanosoma brucei
title_full_unstemmed Subverting lysosomal function in Trypanosoma brucei
title_short Subverting lysosomal function in Trypanosoma brucei
title_sort subverting lysosomal function in trypanosoma brucei
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948668/
https://www.ncbi.nlm.nih.gov/pubmed/27441200
http://dx.doi.org/10.15698/mic2015.08.222
work_keys_str_mv AT alsfordsam subvertinglysosomalfunctionintrypanosomabrucei

Ejemplares similares