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Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo

The aim of the present study was to develop a novel dosage form of multivesicular liposomes for oleanolic acid (OA) to overcome its poor solubility, prolong therapeutic drug levels in the blood, and enhance the antitumor effect on hepatocellular carcinoma. OA-encapsulated multivesicular liposomes (O...

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Detalles Bibliográficos
Autores principales:	Luo, Yuling, Liu, Zhongbing, Zhang, Xiaoqin, Huang, Juan, Yu, Xin, Li, Jinwei, Xiong, Dan, Sun, Xiaoduan, Zhong, Zhirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948731/ https://www.ncbi.nlm.nih.gov/pubmed/27471381 http://dx.doi.org/10.2147/IJN.S108445

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