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Constitutive Expression of GATA4 Dramatically Increases the Cardiogenic Potential of D3 Mouse Embryonic Stem Cells

The transcription factor GATA binding protein 4 (GATA4) is a vital regulator of cardiac programming that acts by inducing the expression of many different genes involved in cardiomyogenesis. Here we generated a D3 mouse embryonic stem cell line that constitutively expresses high levels of GATA4 and...

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Detalles Bibliográficos
Autores principales: Laemmle, Lillian L., Cohen, Justus B., Glorioso, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948750/
https://www.ncbi.nlm.nih.gov/pubmed/27441042
http://dx.doi.org/10.2174/1874070701610010248

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