Immunohistochemical Determination of p53 Protein Overexpression for Predicting p53 Gene Mutations in Hepatocellular Carcinoma: A Meta-Analysis

BACKGROUND: Whether increased expression of the tumor suppressor protein p53 indicates a p53 gene mutation in hepatocellular carcinoma (HCC) remains unclear. We conducted a meta-analysis to determine whether p53 protein overexpression detected by immunohistochemistry (IHC) offers a diagnostic predic...

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Detalles Bibliográficos
Autores principales: Liu, Jiangbo, Li, Wei, Deng, Miao, Liu, Dechun, Ma, Qingyong, Feng, Xiaoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948819/
https://www.ncbi.nlm.nih.gov/pubmed/27428001
http://dx.doi.org/10.1371/journal.pone.0159636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948819/
https://www.ncbi.nlm.nih.gov/pubmed/27428001
http://dx.doi.org/10.1371/journal.pone.0159636

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