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Immunohistochemical Determination of p53 Protein Overexpression for Predicting p53 Gene Mutations in Hepatocellular Carcinoma: A Meta-Analysis

BACKGROUND: Whether increased expression of the tumor suppressor protein p53 indicates a p53 gene mutation in hepatocellular carcinoma (HCC) remains unclear. We conducted a meta-analysis to determine whether p53 protein overexpression detected by immunohistochemistry (IHC) offers a diagnostic predic...

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Detalles Bibliográficos
Autores principales:	Liu, Jiangbo, Li, Wei, Deng, Miao, Liu, Dechun, Ma, Qingyong, Feng, Xiaoshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948819/ https://www.ncbi.nlm.nih.gov/pubmed/27428001 http://dx.doi.org/10.1371/journal.pone.0159636

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