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Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats

BACKGROUND: Iron chelators are used to treat iron overload cardiomyopathy patients. However, a direct comparison of the benefits of three common iron chelators (deferoxamine (DFO), deferiprone (DFP) and deferasirox (DFX)) or an antioxidant (N-acetyl cysteine (NAC)) with a combined DFP and NAC treatm...

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Detalles Bibliográficos
Autores principales:	Wongjaikam, Suwakon, Kumfu, Sirinart, Khamseekaew, Juthamas, Sripetchwandee, Jirapas, Srichairatanakool, Somdet, Fucharoen, Suthat, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948821/ https://www.ncbi.nlm.nih.gov/pubmed/27428732 http://dx.doi.org/10.1371/journal.pone.0159414

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