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HIV-1 Subtype C Mosaic Gag Expressed by BCG and MVA Elicits Persistent Effector T Cell Responses in a Prime-Boost Regimen in Mice
Over 90% of HIV/AIDS positive individuals in sub-Saharan Africa are infected with highly heterogeneous HIV-1 subtype C (HIV-1C) viruses. One of the best ways to reduce the burden of this disease is the development of an affordable and effective prophylactic vaccine. Mosaic immunogens are computation...
Autores principales: | Jongwe, Tsungai Ivai, Chapman, Ros, Douglass, Nicola, Chetty, Shivan, Chege, Gerald, Williamson, Anna-Lise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948879/ https://www.ncbi.nlm.nih.gov/pubmed/27427967 http://dx.doi.org/10.1371/journal.pone.0159141 |
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