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XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice

Transcription factors have an important role in cancer but are difficult targets for the development of tumour therapies. These factors include the Ets family, and in this study Elk3 that is activated by Ras oncogene /Erk signalling, and is involved in angiogenesis, malignant progression and epithel...

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Detalles Bibliográficos
Autores principales:	Semenchenko, Kostyantyn, Wasylyk, Christine, Cheung, Henry, Tourrette, Yves, Maas, Peter, Schalken, Jack A, van der Pluijm, Gabri, Wasylyk, Bohdan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948895/ https://www.ncbi.nlm.nih.gov/pubmed/27427904 http://dx.doi.org/10.1371/journal.pone.0159531

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