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Inhibition of Advanced Glycation End Products (AGEs) Accumulation by Pyridoxamine Modulates Glomerular and Mesangial Cell Estrogen Receptor α Expression in Aged Female Mice

Age-related increases in oxidant stress (OS) play a role in regulation of estrogen receptor (ER) expression in the kidneys. In this study, we establish that in vivo 17β-estradiol (E(2)) replacement can no longer upregulate glomerular ER expression by 21 months of age in female mice (anestrous). We h...

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Detalles Bibliográficos
Autores principales:	Pereira-Simon, Simone, Rubio, Gustavo A., Xia, Xiaomei, Cai, Weijing, Choi, Rhea, Striker, Gary E., Elliot, Sharon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948910/ https://www.ncbi.nlm.nih.gov/pubmed/27428057 http://dx.doi.org/10.1371/journal.pone.0159666

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