Dried Blood Spot Methodology in Combination With Liquid Chromatography/Tandem Mass Spectrometry Facilitates the Monitoring of Teriflunomide

BACKGROUND: Teriflunomide, a once-daily oral immunomodulator approved for treatment of relapsing-remitting multiple sclerosis, is eliminated slowly from plasma. If necessary to rapidly lower plasma concentrations of teriflunomide, an accelerated elimination procedure using cholestyramine or activate...

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Detalles Bibliográficos
Autores principales: Filali-Ansary, Aziz, Lunven, Catherine, Turpault, Sandrine, Beyer, Yann-Joel, O'Brien, Amy, Delfolie, Astrid, Boyanova, Neli, Sanderink, Ger-Jan, Baldinetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949010/
https://www.ncbi.nlm.nih.gov/pubmed/27015245
http://dx.doi.org/10.1097/FTD.0000000000000302

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