Cargando…
Human Phase 1 trial of low-dose inactivated seasonal influenza vaccine formulated with Advax™ delta inulin adjuvant
Influenza vaccines are usually non-adjuvanted but addition of adjuvant may improve immunogenicity and permit dose-sparing, critical for vaccine supply in the event of an influenza pandemic. The aim of this first-in-man study was to determine the effect of delta inulin adjuvant on the safety and immu...
Autores principales: | Gordon, David L., Sajkov, Dimitar, Honda-Okubo, Yoshikazu, Wilks, Samuel H., Aban, Malet, Barr, Ian G., Petrovsky, Nikolai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949042/ https://www.ncbi.nlm.nih.gov/pubmed/27342914 http://dx.doi.org/10.1016/j.vaccine.2016.05.071 |
Ejemplares similares
-
Panblok-H1+advax H1N1/2009pdm vaccine: Insights into rapid development of a delta inulin adjuvanted recombinant pandemic influenza vaccine
por: Honda-Okubo, Yoshikazu, et al.
Publicado: (2017) -
Advax delta inulin adjuvant overcomes immune immaturity in neonatal mice thereby allowing single–dose influenza vaccine protection
por: Honda-Okubo, Yoshikazu, et al.
Publicado: (2015) -
Delta Inulin Adjuvant Enhances Plasmablast Generation, Expression of Activation-Induced Cytidine Deaminase and B-Cell Affinity Maturation in Human Subjects Receiving Seasonal Influenza Vaccine
por: Li, Lei, et al.
Publicado: (2015) -
Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
por: Hayashi, Masayuki, et al.
Publicado: (2016) -
Advax-CpG Adjuvant Provides Antigen Dose-Sparing and Enhanced Immunogenicity for Inactivated Poliomyelitis Virus Vaccines
por: Honda-Okubo, Yoshikazu, et al.
Publicado: (2021)