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Time to move the fat
In this issue of Genes & Development, Dowen and colleagues (pp. 1515–1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobili...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949320/ https://www.ncbi.nlm.nih.gov/pubmed/27401550 http://dx.doi.org/10.1101/gad.285460.116 |
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author | Weaver, Benjamin P. Sewell, Aileen K. Han, Min |
author_facet | Weaver, Benjamin P. Sewell, Aileen K. Han, Min |
author_sort | Weaver, Benjamin P. |
collection | PubMed |
description | In this issue of Genes & Development, Dowen and colleagues (pp. 1515–1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling from the hypodermis (epidermis) to the intestine to promote reproductive success in the germline. |
format | Online Article Text |
id | pubmed-4949320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Cold Spring Harbor Laboratory Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-49493202017-01-01 Time to move the fat Weaver, Benjamin P. Sewell, Aileen K. Han, Min Genes Dev Outlook In this issue of Genes & Development, Dowen and colleagues (pp. 1515–1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling from the hypodermis (epidermis) to the intestine to promote reproductive success in the germline. Cold Spring Harbor Laboratory Press 2016-07-01 /pmc/articles/PMC4949320/ /pubmed/27401550 http://dx.doi.org/10.1101/gad.285460.116 Text en © 2016 Weaver et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Outlook Weaver, Benjamin P. Sewell, Aileen K. Han, Min Time to move the fat |
title | Time to move the fat |
title_full | Time to move the fat |
title_fullStr | Time to move the fat |
title_full_unstemmed | Time to move the fat |
title_short | Time to move the fat |
title_sort | time to move the fat |
topic | Outlook |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949320/ https://www.ncbi.nlm.nih.gov/pubmed/27401550 http://dx.doi.org/10.1101/gad.285460.116 |
work_keys_str_mv | AT weaverbenjaminp timetomovethefat AT sewellaileenk timetomovethefat AT hanmin timetomovethefat |