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Time to move the fat

In this issue of Genes & Development, Dowen and colleagues (pp. 1515–1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobili...

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Detalles Bibliográficos
Autores principales: Weaver, Benjamin P., Sewell, Aileen K., Han, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949320/
https://www.ncbi.nlm.nih.gov/pubmed/27401550
http://dx.doi.org/10.1101/gad.285460.116
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author Weaver, Benjamin P.
Sewell, Aileen K.
Han, Min
author_facet Weaver, Benjamin P.
Sewell, Aileen K.
Han, Min
author_sort Weaver, Benjamin P.
collection PubMed
description In this issue of Genes & Development, Dowen and colleagues (pp. 1515–1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling from the hypodermis (epidermis) to the intestine to promote reproductive success in the germline.
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spelling pubmed-49493202017-01-01 Time to move the fat Weaver, Benjamin P. Sewell, Aileen K. Han, Min Genes Dev Outlook In this issue of Genes & Development, Dowen and colleagues (pp. 1515–1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling from the hypodermis (epidermis) to the intestine to promote reproductive success in the germline. Cold Spring Harbor Laboratory Press 2016-07-01 /pmc/articles/PMC4949320/ /pubmed/27401550 http://dx.doi.org/10.1101/gad.285460.116 Text en © 2016 Weaver et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Outlook
Weaver, Benjamin P.
Sewell, Aileen K.
Han, Min
Time to move the fat
title Time to move the fat
title_full Time to move the fat
title_fullStr Time to move the fat
title_full_unstemmed Time to move the fat
title_short Time to move the fat
title_sort time to move the fat
topic Outlook
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949320/
https://www.ncbi.nlm.nih.gov/pubmed/27401550
http://dx.doi.org/10.1101/gad.285460.116
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