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Oxidative stress-mediated intrinsic apoptosis in human promyelocytic leukemia HL-60 cells induced by organic arsenicals

Arsenic trioxide has shown the excellent therapeutic efficiency for acute promyelocytic leukemia. Nowadays, more and more research focuses on the design of the arsenic drugs, especially organic arsenicals, and on the mechanism of the inducing cell death. Here we have synthesized some organic arsenic...

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Detalles Bibliográficos
Autores principales: Fan, Xiao-Yang, Chen, Xin-You, Liu, Yu-Jiao, Zhong, Hui-Min, Jiang, Feng-Lei, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949440/
https://www.ncbi.nlm.nih.gov/pubmed/27432798
http://dx.doi.org/10.1038/srep29865

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