Cargando…
Bile signalling promotes chronic respiratory infections and antibiotic tolerance
Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinning the chronic inflammation and eventual lung decline that are characteristic of respiratory disease. Recently, bile acid aspiration has emerged as a major comorbidity associated with a range of lung...
Autores principales: | Reen, F. Jerry, Flynn, Stephanie, Woods, David F., Dunphy, Niall, Chróinín, Muireann Ní, Mullane, David, Stick, Stephen, Adams, Claire, O’Gara, Fergal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949476/ https://www.ncbi.nlm.nih.gov/pubmed/27432520 http://dx.doi.org/10.1038/srep29768 |
Ejemplares similares
-
Respiratory Pathogens Adopt a Chronic Lifestyle in Response to Bile
por: Reen, F. Jerry, et al.
Publicado: (2012) -
Systems Biology and Bile Acid Signalling in Microbiome-Host Interactions in the Cystic Fibrosis Lung
por: Woods, David F., et al.
Publicado: (2021) -
Exposure to Bile Leads to the Emergence of Adaptive Signaling Variants in the Opportunistic Pathogen Pseudomonas aeruginosa
por: Flynn, Stephanie, et al.
Publicado: (2019) -
Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients
por: Flynn, Stephanie, et al.
Publicado: (2020) -
The Detection of Bile Acids in the Lungs of Paediatric Cystic Fibrosis Patients Is Associated with Altered Inflammatory Patterns
por: Caparrós-Martín, Jose A., et al.
Publicado: (2020)