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Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection
BACKGROUND: Chronic hepatitis C virus (HCV) infection of the liver with either genotype 1 or genotype 3 gives rise to distinct pathologies, and the two viral genotypes respond differently to antiviral therapy. METHODS: To understand these clinical differences, we compared gene transcription profiles...
Autores principales: | Robinson, Mark W., Aranday‐Cortes, Elihu, Gatherer, Derek, Swann, Rachael, Liefhebber, Jolanda M. P., Filipe, Ana Da Silva, Sigruener, Alex, Barclay, Stephen T., Mills, Peter R., Patel, Arvind H., McLauchlan, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949513/ https://www.ncbi.nlm.nih.gov/pubmed/25800823 http://dx.doi.org/10.1111/liv.12830 |
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