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Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature
INTRODUCTION: Chronic suppurative hidradenitis (CSH) is a benign condition that can affect the perineal region and often leads to the formation of abscesses and fistulas. It is rare for CSH to undergo malignant degeneration into mucinous adenocarcinoma. PRESENTATION OF CASE: We report a case of a 55...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949808/ https://www.ncbi.nlm.nih.gov/pubmed/27424105 http://dx.doi.org/10.1016/j.ijscr.2016.06.039 |
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author | Mukai, Natalia Pinheiro, Lílian Vital Ayrizono, Maria de Lourdes Setsuko Barreiro, Guilherme Cardinali Kharmandayan, Paulo Akinaga, Mariana Hanayo Bento, Adriano Mesquita Martinez, Carlos Augusto Real de Carvalho, Rita Barbosa Ward, Marc Coy, Cláudio Saddy Rodrigues Leal, Raquel Franco |
author_facet | Mukai, Natalia Pinheiro, Lílian Vital Ayrizono, Maria de Lourdes Setsuko Barreiro, Guilherme Cardinali Kharmandayan, Paulo Akinaga, Mariana Hanayo Bento, Adriano Mesquita Martinez, Carlos Augusto Real de Carvalho, Rita Barbosa Ward, Marc Coy, Cláudio Saddy Rodrigues Leal, Raquel Franco |
author_sort | Mukai, Natalia |
collection | PubMed |
description | INTRODUCTION: Chronic suppurative hidradenitis (CSH) is a benign condition that can affect the perineal region and often leads to the formation of abscesses and fistulas. It is rare for CSH to undergo malignant degeneration into mucinous adenocarcinoma. PRESENTATION OF CASE: We report a case of a 55-year-old male patient with perineal CSH who suffered worsening long-term pain despite multiple surgical procedures to alleviate his symptoms. Pelvic magnetic resonance imaging (MRI) showed multiloculated cystic lesion on the left side wall of the distal rectum with gluteal extension. Pathological examination revealed mucinous adenocarcinoma. The patient underwent an abdominoperineal resection (APR) of the rectum with cutaneous muscle flap reconstruction. Although histopathological sections showed clear margins, the tumor recurred 6 months following surgery. DISCUSSION: Perineal mucinous adenocarcinoma arising in a patient with CSH is an extremely rare condition. This diagnosis is often difficult, due to the paucity of signs of malignant degeneration as well as the rarity of the disease itself. Surgical resection of the lesions is a well-established approach. In this case, diagnosing the tumor at such a late stage likely compromised his outcome. CONCLUSION: Malignant degeneration to mucinous adenocarcinoma must be suspected in patients with a history of long-term CSH. In such cases, local biopsies and a radiological examination, such as MRI can help in the diagnosis. |
format | Online Article Text |
id | pubmed-4949808 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49498082016-08-03 Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature Mukai, Natalia Pinheiro, Lílian Vital Ayrizono, Maria de Lourdes Setsuko Barreiro, Guilherme Cardinali Kharmandayan, Paulo Akinaga, Mariana Hanayo Bento, Adriano Mesquita Martinez, Carlos Augusto Real de Carvalho, Rita Barbosa Ward, Marc Coy, Cláudio Saddy Rodrigues Leal, Raquel Franco Int J Surg Case Rep Case Report INTRODUCTION: Chronic suppurative hidradenitis (CSH) is a benign condition that can affect the perineal region and often leads to the formation of abscesses and fistulas. It is rare for CSH to undergo malignant degeneration into mucinous adenocarcinoma. PRESENTATION OF CASE: We report a case of a 55-year-old male patient with perineal CSH who suffered worsening long-term pain despite multiple surgical procedures to alleviate his symptoms. Pelvic magnetic resonance imaging (MRI) showed multiloculated cystic lesion on the left side wall of the distal rectum with gluteal extension. Pathological examination revealed mucinous adenocarcinoma. The patient underwent an abdominoperineal resection (APR) of the rectum with cutaneous muscle flap reconstruction. Although histopathological sections showed clear margins, the tumor recurred 6 months following surgery. DISCUSSION: Perineal mucinous adenocarcinoma arising in a patient with CSH is an extremely rare condition. This diagnosis is often difficult, due to the paucity of signs of malignant degeneration as well as the rarity of the disease itself. Surgical resection of the lesions is a well-established approach. In this case, diagnosing the tumor at such a late stage likely compromised his outcome. CONCLUSION: Malignant degeneration to mucinous adenocarcinoma must be suspected in patients with a history of long-term CSH. In such cases, local biopsies and a radiological examination, such as MRI can help in the diagnosis. Elsevier 2016-07-07 /pmc/articles/PMC4949808/ /pubmed/27424105 http://dx.doi.org/10.1016/j.ijscr.2016.06.039 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Mukai, Natalia Pinheiro, Lílian Vital Ayrizono, Maria de Lourdes Setsuko Barreiro, Guilherme Cardinali Kharmandayan, Paulo Akinaga, Mariana Hanayo Bento, Adriano Mesquita Martinez, Carlos Augusto Real de Carvalho, Rita Barbosa Ward, Marc Coy, Cláudio Saddy Rodrigues Leal, Raquel Franco Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature |
title | Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature |
title_full | Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature |
title_fullStr | Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature |
title_full_unstemmed | Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature |
title_short | Mucinous adenocarcinoma associated with chronic suppurative hidradenitis: Report of a case and review of the literature |
title_sort | mucinous adenocarcinoma associated with chronic suppurative hidradenitis: report of a case and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949808/ https://www.ncbi.nlm.nih.gov/pubmed/27424105 http://dx.doi.org/10.1016/j.ijscr.2016.06.039 |
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