Human intrahepatic regulatory T cells are functional, require IL‐2 from effector cells for survival, and are susceptible to Fas ligand‐mediated apoptosis

Regulatory T cells (T(reg)) suppress T effector cell proliferation and maintain immune homeostasis. Autoimmune liver diseases persist despite high frequencies of T(reg) in the liver, suggesting that the local hepatic microenvironment might affect T(reg) stability, survival, and function. We hypothes...

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Detalles Bibliográficos
Autores principales: Chen, Yung‐Yi, Jeffery, Hannah C., Hunter, Stuart, Bhogal, Ricky, Birtwistle, Jane, Braitch, Manjit Kaur, Roberts, Sheree, Ming, Mikaela, Hannah, Jack, Thomas, Clare, Adali, Gupse, Hübscher, Stefan G., Syn, Wing‐Kin, Afford, Simon, Lalor, Patricia F., Adams, David H., Oo, Ye H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Autoimmune, Cholestatic and Biliary Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950043/
https://www.ncbi.nlm.nih.gov/pubmed/26928938
http://dx.doi.org/10.1002/hep.28517

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