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Services for people at high risk improve outcomes in patients with first episode psychosis

OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospecti...

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Autores principales: Fusar‐Poli, P., Díaz‐Caneja, C. M., Patel, R., Valmaggia, L., Byrne, M., Garety, P., Shetty, H., Broadbent, M., Stewart, R., McGuire, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950045/
https://www.ncbi.nlm.nih.gov/pubmed/26358300
http://dx.doi.org/10.1111/acps.12480
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author Fusar‐Poli, P.
Díaz‐Caneja, C. M.
Patel, R.
Valmaggia, L.
Byrne, M.
Garety, P.
Shetty, H.
Broadbent, M.
Stewart, R.
McGuire, P.
author_facet Fusar‐Poli, P.
Díaz‐Caneja, C. M.
Patel, R.
Valmaggia, L.
Byrne, M.
Garety, P.
Shetty, H.
Broadbent, M.
Stewart, R.
McGuire, P.
author_sort Fusar‐Poli, P.
collection PubMed
description OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospective study comparing duration of hospital admission, referral‐to‐diagnosis time, need for compulsory hospital admission and frequency of admission in patients with FEP who initially presented to a high‐risk service (n = 164) to patients with FEP who initially presented to conventional mental health services (n = 2779). Regression models were performed, controlling for several confounders. RESULTS: FEP patients who had presented to a high‐risk service spent 17 fewer days in hospital [95% CI: −33.7 to (−0.3)], had a shorter referral‐to‐diagnosis time [B coefficient −74.5 days, 95% CI: −101.9 to −(47.1)], a lower frequency of admission [IRR: 0.49 (95% CI: 0.39–0.61)] and a lower likelihood of compulsory admission [OR: 0.52 (95% CI: 0.34–0.81)] in the 24 months following referral, as compared to FEP patients who were first diagnosed at conventional services. CONCLUSION: Services for people at high risk for psychosis are associated with better clinical outcomes in patients who are already psychotic.
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spelling pubmed-49500452016-07-28 Services for people at high risk improve outcomes in patients with first episode psychosis Fusar‐Poli, P. Díaz‐Caneja, C. M. Patel, R. Valmaggia, L. Byrne, M. Garety, P. Shetty, H. Broadbent, M. Stewart, R. McGuire, P. Acta Psychiatr Scand Original Articles OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospective study comparing duration of hospital admission, referral‐to‐diagnosis time, need for compulsory hospital admission and frequency of admission in patients with FEP who initially presented to a high‐risk service (n = 164) to patients with FEP who initially presented to conventional mental health services (n = 2779). Regression models were performed, controlling for several confounders. RESULTS: FEP patients who had presented to a high‐risk service spent 17 fewer days in hospital [95% CI: −33.7 to (−0.3)], had a shorter referral‐to‐diagnosis time [B coefficient −74.5 days, 95% CI: −101.9 to −(47.1)], a lower frequency of admission [IRR: 0.49 (95% CI: 0.39–0.61)] and a lower likelihood of compulsory admission [OR: 0.52 (95% CI: 0.34–0.81)] in the 24 months following referral, as compared to FEP patients who were first diagnosed at conventional services. CONCLUSION: Services for people at high risk for psychosis are associated with better clinical outcomes in patients who are already psychotic. John Wiley and Sons Inc. 2015-09-11 2016-01 /pmc/articles/PMC4950045/ /pubmed/26358300 http://dx.doi.org/10.1111/acps.12480 Text en © 2015 The Authors. Acta Psychiatrica Scandinavica Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Fusar‐Poli, P.
Díaz‐Caneja, C. M.
Patel, R.
Valmaggia, L.
Byrne, M.
Garety, P.
Shetty, H.
Broadbent, M.
Stewart, R.
McGuire, P.
Services for people at high risk improve outcomes in patients with first episode psychosis
title Services for people at high risk improve outcomes in patients with first episode psychosis
title_full Services for people at high risk improve outcomes in patients with first episode psychosis
title_fullStr Services for people at high risk improve outcomes in patients with first episode psychosis
title_full_unstemmed Services for people at high risk improve outcomes in patients with first episode psychosis
title_short Services for people at high risk improve outcomes in patients with first episode psychosis
title_sort services for people at high risk improve outcomes in patients with first episode psychosis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950045/
https://www.ncbi.nlm.nih.gov/pubmed/26358300
http://dx.doi.org/10.1111/acps.12480
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