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Services for people at high risk improve outcomes in patients with first episode psychosis
OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospecti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950045/ https://www.ncbi.nlm.nih.gov/pubmed/26358300 http://dx.doi.org/10.1111/acps.12480 |
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author | Fusar‐Poli, P. Díaz‐Caneja, C. M. Patel, R. Valmaggia, L. Byrne, M. Garety, P. Shetty, H. Broadbent, M. Stewart, R. McGuire, P. |
author_facet | Fusar‐Poli, P. Díaz‐Caneja, C. M. Patel, R. Valmaggia, L. Byrne, M. Garety, P. Shetty, H. Broadbent, M. Stewart, R. McGuire, P. |
author_sort | Fusar‐Poli, P. |
collection | PubMed |
description | OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospective study comparing duration of hospital admission, referral‐to‐diagnosis time, need for compulsory hospital admission and frequency of admission in patients with FEP who initially presented to a high‐risk service (n = 164) to patients with FEP who initially presented to conventional mental health services (n = 2779). Regression models were performed, controlling for several confounders. RESULTS: FEP patients who had presented to a high‐risk service spent 17 fewer days in hospital [95% CI: −33.7 to (−0.3)], had a shorter referral‐to‐diagnosis time [B coefficient −74.5 days, 95% CI: −101.9 to −(47.1)], a lower frequency of admission [IRR: 0.49 (95% CI: 0.39–0.61)] and a lower likelihood of compulsory admission [OR: 0.52 (95% CI: 0.34–0.81)] in the 24 months following referral, as compared to FEP patients who were first diagnosed at conventional services. CONCLUSION: Services for people at high risk for psychosis are associated with better clinical outcomes in patients who are already psychotic. |
format | Online Article Text |
id | pubmed-4950045 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-49500452016-07-28 Services for people at high risk improve outcomes in patients with first episode psychosis Fusar‐Poli, P. Díaz‐Caneja, C. M. Patel, R. Valmaggia, L. Byrne, M. Garety, P. Shetty, H. Broadbent, M. Stewart, R. McGuire, P. Acta Psychiatr Scand Original Articles OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospective study comparing duration of hospital admission, referral‐to‐diagnosis time, need for compulsory hospital admission and frequency of admission in patients with FEP who initially presented to a high‐risk service (n = 164) to patients with FEP who initially presented to conventional mental health services (n = 2779). Regression models were performed, controlling for several confounders. RESULTS: FEP patients who had presented to a high‐risk service spent 17 fewer days in hospital [95% CI: −33.7 to (−0.3)], had a shorter referral‐to‐diagnosis time [B coefficient −74.5 days, 95% CI: −101.9 to −(47.1)], a lower frequency of admission [IRR: 0.49 (95% CI: 0.39–0.61)] and a lower likelihood of compulsory admission [OR: 0.52 (95% CI: 0.34–0.81)] in the 24 months following referral, as compared to FEP patients who were first diagnosed at conventional services. CONCLUSION: Services for people at high risk for psychosis are associated with better clinical outcomes in patients who are already psychotic. John Wiley and Sons Inc. 2015-09-11 2016-01 /pmc/articles/PMC4950045/ /pubmed/26358300 http://dx.doi.org/10.1111/acps.12480 Text en © 2015 The Authors. Acta Psychiatrica Scandinavica Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Fusar‐Poli, P. Díaz‐Caneja, C. M. Patel, R. Valmaggia, L. Byrne, M. Garety, P. Shetty, H. Broadbent, M. Stewart, R. McGuire, P. Services for people at high risk improve outcomes in patients with first episode psychosis |
title | Services for people at high risk improve outcomes in patients with first episode psychosis |
title_full | Services for people at high risk improve outcomes in patients with first episode psychosis |
title_fullStr | Services for people at high risk improve outcomes in patients with first episode psychosis |
title_full_unstemmed | Services for people at high risk improve outcomes in patients with first episode psychosis |
title_short | Services for people at high risk improve outcomes in patients with first episode psychosis |
title_sort | services for people at high risk improve outcomes in patients with first episode psychosis |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950045/ https://www.ncbi.nlm.nih.gov/pubmed/26358300 http://dx.doi.org/10.1111/acps.12480 |
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