Evaluation of differential effects of metformin treatment in obese children according to pubertal stage and genetic variations: study protocol for a randomized controlled trial

BACKGROUND: Overweight and obesity are considered to be serious public health problems. In pediatric populations, insulin resistance, dyslipidemia, and hypertension associated with obesity occur with increased frequencies. Metformin is an oral anti-hyperglycemic agent that has been demonstrated to b...

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Detalles Bibliográficos
Autores principales: Pastor-Villaescusa, Belén, Caballero-Villarraso, Javier, Cañete, M. Dolores, Hoyos, Raúl, Maldonado, José, Bueno, Gloria, Leis, Rosaura, Gil, Ángel, Cañete, Ramón, Aguilera, Concepción M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950074/
https://www.ncbi.nlm.nih.gov/pubmed/27432166
http://dx.doi.org/10.1186/s13063-016-1403-4

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