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Insights into 6‐Methylsalicylic Acid Bio‐assembly by Using Chemical Probes
Chemical probes capable of reacting with KS (ketosynthase)‐bound biosynthetic intermediates were utilized for the investigation of the model type I iterative polyketide synthase 6‐methylsalicylic acid synthase (6‐MSAS) in vivo and in vitro. From the fermentation of fungal and bacterial 6‐MSAS hosts...
Autores principales: | Parascandolo, James S., Havemann, Judith, Potter, Helen K., Huang, Fanglu, Riva, Elena, Connolly, Jack, Wilkening, Ina, Song, Lijiang, Leadlay, Peter F., Tosin, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950124/ https://www.ncbi.nlm.nih.gov/pubmed/27478274 http://dx.doi.org/10.1002/ange.201509038 |
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