Cargando…

The role of formyl peptide receptor 1 (FPR1) in neuroblastoma tumorigenesis

BACKGROUND: Formyl peptide receptor 1 (FPR1) is a G protein-coupled receptor mainly expressed by the cells of myeloid origin, where it mediates the innate immune response to bacterial formylated peptides. High expression of FPR1 has been detected in various cancers but the function of FPR1 in tumori...

Descripción completa

Detalles Bibliográficos
Autores principales:	Snapkov, Igor, Öqvist, Carl Otto, Figenschau, Yngve, Kogner, Per, Johnsen, John Inge, Sveinbjørnsson, Baldur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950242/ https://www.ncbi.nlm.nih.gov/pubmed/27432059 http://dx.doi.org/10.1186/s12885-016-2545-1

Ejemplares similares

FITC Conjugation Markedly Enhances Hepatic Clearance of N-Formyl Peptides
por: Øie, Cristina Ionica, et al.
Publicado: (2016)

Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo
por: Tümmler, Conny, et al.
Publicado: (2017)

Immune suppression by myeloid-derived suppressor cells, MDSCs, in MYCN-driven neuroblastoma provides a potential target for cancer immunotherapy
por: Eissler, Nina, et al.
Publicado: (2014)

Formyl peptide receptor-1 (FPR1) represses intestinal oncogenesis
por: Le Naour, Julie, et al.
Publicado: (2023)

SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells In Vitro
por: Tümmler, Conny, et al.
Publicado: (2019)

Regulation of the Formyl Peptide Receptor 1 (FPR1) Gene in Primary Human Macrophages
por: Gemperle, Claudio, et al.
Publicado: (2012)

Autocrine Prostaglandin E(2) Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma
por: Rasmuson, Agnes, et al.
Publicado: (2012)

Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1
por: Lammers, Karen M., et al.
Publicado: (2015)

Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma
por: Hald, Øyvind H., et al.
Publicado: (2018)

Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis
por: Crocetti, Letizia, et al.
Publicado: (2021)

Formyl Peptide Receptor (FPR)1 Modulation by Resveratrol in an LPS-Induced Neuroinflammatory Animal Model
por: Calvello, Rosa, et al.
Publicado: (2021)

The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytes
por: Carlson, Lena-Maria, et al.
Publicado: (2013)

Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21-157)
por: Berg, Vivian, et al.
Publicado: (2010)

Role of formyl peptide receptor 2 (FPR2) in the normal brain and in neurological conditions
por: Ong, Wei-Yi, et al.
Publicado: (2019)

Redox signaling regulates commensal mediated mucosal homeostasis and restitution and requires formyl peptide receptor 1 (FPR1)
por: Alam, Ashfaqul, et al.
Publicado: (2013)

Distinct Signaling Cascades Elicited by Different Formyl Peptide Receptor 2 (FPR2) Agonists
por: Cattaneo, Fabio, et al.
Publicado: (2013)

The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations
por: Yuan, Shuguang, et al.
Publicado: (2012)

An independent predictor of poor prognosis in locally advanced rectal cancer: rs867228 in formyl peptide receptor 1 (FPR1)
por: Chiang, Shu-Fen, et al.
Publicado: (2021)

Acute-serum amyloid A and A-SAA-derived peptides as formyl peptide receptor (FPR) 2 ligands
por: Abouelasrar Salama, Sara, et al.
Publicado: (2023)

The formyl peptide receptor agonist FPRa14 induces differentiation of Neuro2a mouse neuroblastoma cells into multiple distinct morphologies which can be specifically inhibited with FPR antagonists and FPR knockdown using siRNA
por: Cussell, Peter J. G., et al.
Publicado: (2019)

V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins
por: Zhou, Caihong, et al.
Publicado: (2013)

PPM1D Is a Therapeutic Target in Childhood Neural Tumors
por: Milosevic, Jelena, et al.
Publicado: (2021)

Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome
por: D’Amico, Ramona, et al.
Publicado: (2020)

Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas
por: Kiss, Nimrod B, et al.
Publicado: (2012)

The beneficial effects of commensal E. coli for colon epithelial cell recovery are related with Formyl peptide receptor 2 (Fpr2) in epithelial cells
por: Chen, Keqiang, et al.
Publicado: (2023)

N-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells—An In Vitro Model for Early Inflammatory Profiling of Schwann Cells
por: Korimová, Andrea, et al.
Publicado: (2020)

Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth
por: Kock, Anna, et al.
Publicado: (2018)

Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
por: Wickström, Malin, et al.
Publicado: (2015)

The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Exhibits Anti-Inflammatory Activity in LPS-Stimulated Organotypic Hippocampal Cultures
por: Trojan, Ewa, et al.
Publicado: (2021)

Correction: The beneficial effects of commensal E. coli for colon epithelial cell recovery are related with Formyl peptide receptor 2 (Fpr2) in epithelial cells
por: Chen, Keqiang, et al.
Publicado: (2023)

Differential activation of polymorphisms of the formyl peptide receptor by formyl peptides
por: Mills, John S.
Publicado: (2007)

Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
por: Liu, Fu-Chao, et al.
Publicado: (2017)

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2
por: Zhuang, Youwen, et al.
Publicado: (2022)

Planar cell polarity gene expression correlates with tumor cell viability and prognostic outcome in neuroblastoma
por: Dyberg, Cecilia, et al.
Publicado: (2016)

Formyl Met-Leu-Phe-Stimulated FPR1 Phosphorylation in Plate-Adherent Human Neutrophils: Enhanced Proteolysis but Lack of Inhibition by Platelet-Activating Factor
por: Jesaitis, Algirdas J., et al.
Publicado: (2018)

The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1–42)-Induced Neuroinflammation in Mouse Models of Alzheimer’s Disease
por: Trojan, Ewa, et al.
Publicado: (2021)

Intersectin 1 is required for neuroblastoma tumorigenesis
por: Russo, Angela, et al.
Publicado: (2012)

The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma
por: Rasheed, Kashif, et al.
Publicado: (2022)

FPR Ligands
por: Liu, Ying, et al.
Publicado: (2013)

Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase
por: Hiyoshi, H, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_klkfnnomd5b067l50dhp8d8phk