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Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma

The presence of mutations in the KRAS gene is a predictor of a poor clinical response to EGFR-targeted agents in patients affected by colorectal cancer (CRC), but its significance as a global prognostic factor remains unclear. The aim of the present study was to evaluate the impact of the KRAS mutat...

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Detalles Bibliográficos
Autores principales: Palomba, Grazia, Cossu, Antonio, Paliogiannis, Panagiotis, Pazzola, Antonio, Baldino, Giovanni, Scartozzi, Mario, Ionta, Maria Teresa, Ortu, Salvatore, Capelli, Francesca, Lanzillo, Annamaria, Sedda, Tito, Sanna, Giovanni, Barca, Michela, Virdis, Luciano, Budroni, Mario, Palmieri, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950545/
https://www.ncbi.nlm.nih.gov/pubmed/27446446
http://dx.doi.org/10.3892/ol.2016.4798