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AT-101 enhances gefitinib sensitivity in non-small cell lung cancer with EGFR T790M mutations

BACKGROUND: Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) have become the standard care of patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC), development of acquired resistance is inevitable. A secondary mutation of threonine 790 (T790M) is asso...

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Detalles Bibliográficos
Autores principales:	Zhao, Ren, Zhou, Shun, Xia, Bing, Zhang, Cui-ying, Hai, Ping, Zhe, Hong, Wang, Yan-yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950625/ https://www.ncbi.nlm.nih.gov/pubmed/27431492 http://dx.doi.org/10.1186/s12885-016-2519-3

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