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Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes

BACKGROUND: Streptococcus pneumoniae causes several human diseases, including pneumonia and meningitis, in which pathology is associated with an excessive inflammatory response. A major inducer of this response is the cholesterol dependent pneumococcal toxin, pneumolysin. Here, we measured the amoun...

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Detalles Bibliográficos
Autores principales: Baumgartner, Denja, Aebi, Suzanne, Grandgirard, Denis, Leib, Stephen L., Draeger, Annette, Babiychuk, Eduard, Hathaway, Lucy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950757/
https://www.ncbi.nlm.nih.gov/pubmed/27430279
http://dx.doi.org/10.1186/s12866-016-0777-5