Cargando…

Prolonged repeated vaccine immuno-chemotherapy induces long-term clinical responses and survival for advanced metastatic melanoma

BACKGROUND: Repetitive long-term Vaccinia Melanoma Cell Lysate (VMCL) vaccination schedules have proved clinically effective in producing Complete Responses and strong durable survivals for up to 6.1 years in a previous study of patients with advanced Stage IV and Stage IIIc melanoma. These studies...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coventry, Brendon J, Lilly, Carrie A, Hersey, Peter, Michele, Antonio, Bright, Richard J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950896/ https://www.ncbi.nlm.nih.gov/pubmed/27437102 http://dx.doi.org/10.1186/2051-1426-2-9

Ejemplares similares

Long-term survival in advanced melanoma patients using repeated therapies: successive immunomodulation improving the odds?
por: Coventry, Brendon J, et al.
Publicado: (2015)

Isolated limb infusion chemotherapy for melanoma: an overview of early experience at the Adelaide Melanoma Unit
por: Giles, Mitchell H, et al.
Publicado: (2013)

Prolonged survival in metastatic colorectal cancer following chemotherapy
por: Paul, Doru, et al.
Publicado: (2014)

Clinical outcomes of Interleukin-2 therapy in advanced cancer: meta-analysis of over 62 trials
por: Coventry, Brendon J, et al.
Publicado: (2013)

Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma
por: Guttà, Cristiano, et al.
Publicado: (2020)

Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation
por: Coventry, Brendon J, et al.
Publicado: (2012)

Histone Deacetylase Inhibitors to Overcome Resistance to Targeted and Immuno Therapy in Metastatic Melanoma
por: Yeon, Minjeong, et al.
Publicado: (2020)

Multiple primary malignancies and prolonged survival in a patient with widespread metastatic cutaneous melanoma
por: Rose, Anna M., et al.
Publicado: (2018)

Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma
por: Thompson, John F., et al.
Publicado: (2014)

Therapeutic options for chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review
por: Bright, Richard J, et al.
Publicado: (2014)

Prolonged survival with systemic chemotherapy in an advanced malignant mesothelioma: A case report
por: Elghali, Mohamed Amine, et al.
Publicado: (2021)

Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients
por: Adamik, Juraj, et al.
Publicado: (2023)

Prolonged survival of a patient with metastatic leptomeningeal melanoma treated with BRAF inhibition-based therapy: a case report
por: Kim, Dae Won, et al.
Publicado: (2015)

Long-term Survival after Metastatic Childhood Melanoma
por: Larsen, Anne Kristine, et al.
Publicado: (2014)

Metastatic insulinoma – prolonged survival after multimodal approach
por: Hagel, Alexander F., et al.
Publicado: (2011)

The Predicted Impact of Ipilimumab Usage on Survival in Previously Treated Advanced or Metastatic Melanoma in the UK
por: Larkin, James, et al.
Publicado: (2015)

A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy
por: Kefford, Richard F, et al.
Publicado: (2010)

Cutaneous malignant melanoma incidence is strongly associated with European depigmented skin type regardless of ambient ultraviolet radiation levels: evidence from Worldwide population-based data
por: You, Wenpeng, et al.
Publicado: (2022)

Treatment of Advanced Metastatic Melanoma
por: Quaglino, Pietro, et al.
Publicado: (2021)

Combined targeted therapy and immunotherapy in the treatment of advanced melanoma
por: Wilmott, James S., et al.
Publicado: (2012)

Decreased survival in patients treated by chemotherapy after targeted therapy compared to immunotherapy in metastatic melanoma
por: Mangin, Marie‐Alix, et al.
Publicado: (2021)

Major advancements in metastatic breast cancer treatment: when expanding options means prolonging survival
por: Miglietta, F., et al.
Publicado: (2022)

Economic Evaluation of Single versus Combination Immuno-Oncology Therapies: Application of a Novel Modelling Approach in Metastatic Melanoma
por: Gibson, Eddie J, et al.
Publicado: (2020)

Immune profiling in human breast cancer is predictive of 5- and 10-year survival.
por: Coventry, Brendon, et al.
Publicado: (2015)

Investigation of female survival benefit in metastatic melanoma
por: Richardson, B, et al.
Publicado: (1999)

Clinical determinants of long-term survival in metastatic uveal melanoma
por: Koch, Elias A. T., et al.
Publicado: (2021)

Energy balance in patients with advanced NSCLC, metastatic melanoma and metastatic breast cancer receiving chemotherapy – a longitudinal study
por: Harvie, M N, et al.
Publicado: (2005)

Palliative Radiotherapy in the Presence of Well-Controlled Metastatic Disease after Initial Chemotherapy May Prolong Survival in Patients with Metastatic Esophageal and Gastric Cancer
por: Hingorani, Mohan, et al.
Publicado: (2015)

Immuno-oncology approaches in uveal melanoma: tebentafusp and beyond
por: Gerard, C., et al.
Publicado: (2023)

Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001
por: Hamid, O, et al.
Publicado: (2019)

Therapeutic vaccination immunomodulation: forming the basis of all cancer immunotherapy
por: Coventry, Brendon J.
Publicado: (2019)

Pembrolizumab: First in Class for Treatment of Metastatic Melanoma
por: Barnhart, Carrie
Publicado: (2015)

Mathematical modeling of immune kinetics in advanced cancer through meta-analyses of complete response rates: immune synchronisation emerges as the likely key determinant of clinical response
por: Ashdown, Martin L, et al.
Publicado: (2013)

Advancing translational research for colorectal immuno-oncology
por: Thomas, Elaine M., et al.
Publicado: (2023)

A Descriptive Study of Repeated Hospitalizations and Survival of Patients with Metastatic Melanoma in the Northern Italian Region during 2004–2019
por: Mannucci, Matilde, et al.
Publicado: (2023)

Metastatic colorectal cancer-prolonging overall survival with targeted therapies
por: Dattatreya, Satya
Publicado: (2013)

Evolving impact of long-term survival results on metastatic melanoma treatment
por: Michielin, Olivier, et al.
Publicado: (2020)

Survival rates of patients with metastatic malignant melanoma
por: Sandru, A, et al.
Publicado: (2014)

Bleomycin electrochemotherapy for the management of locally advanced metastatic melanoma: Two notable clinical cases potentially indicating a greater therapeutic role in the era of targeted and immuno-therapy
por: Gallagher, Michael, et al.
Publicado: (2020)

Validation of an Accurate Automated Multiplex Immunofluorescence Method for Immuno-Profiling Melanoma
por: Yaseen, Zarwa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nl9u12idhavhsi0dg18mf67g1s