A core viral protein binds host nucleosomes to sequester immune danger signals

Viral proteins mimic host protein structure and function to redirect cellular processes and subvert innate defenses(1). Small basic proteins compact and regulate both viral and cellular DNA genomes. Nucleosomes are the repeating units of cellular chromatin and play an important role in innate immune...

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Detalles Bibliográficos
Autores principales: Avgousti, Daphne C., Herrmann, Christin, Kulej, Katarzyna, Pancholi, Neha J., Sekulic, Nikolina, Petrescu, Joana, Molden, Rosalynn C., Blumenthal, Daniel, Paris, Andrew J., Reyes, Emigdio D., Ostapchuk, Philomena, Hearing, Patrick, Seeholzer, Steven H., Worthen, G. Scott, Black, Ben E., Garcia, Benjamin A., Weitzman, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950998/
https://www.ncbi.nlm.nih.gov/pubmed/27362237
http://dx.doi.org/10.1038/nature18317

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