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Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study

American Heart Association cardiovascular health metrics are intimately related to cardiovascular diseases. Acting as a key independent risk factor for high morbidity and mortality of cardiovascular diseases, hypertension and its relationship between health status get urgent attention. While the inf...

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Autores principales: Gao, Fei, Liu, Xiaoxue, Wang, Xizhu, Chen, Shouhua, Shi, Jihong, Zhang, Ying, Wu, Shouling, Cai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951012/
https://www.ncbi.nlm.nih.gov/pubmed/27434049
http://dx.doi.org/10.1371/journal.pone.0158869
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author Gao, Fei
Liu, Xiaoxue
Wang, Xizhu
Chen, Shouhua
Shi, Jihong
Zhang, Ying
Wu, Shouling
Cai, Jun
author_facet Gao, Fei
Liu, Xiaoxue
Wang, Xizhu
Chen, Shouhua
Shi, Jihong
Zhang, Ying
Wu, Shouling
Cai, Jun
author_sort Gao, Fei
collection PubMed
description American Heart Association cardiovascular health metrics are intimately related to cardiovascular diseases. Acting as a key independent risk factor for high morbidity and mortality of cardiovascular diseases, hypertension and its relationship between health status get urgent attention. While the influence of individual health status changes and the future risk of new-onset hypertension is rarely understood, the present study applied this construct to assess the changes of cardiovascular health status and the morbidity of hypertension in Kailuan cohort study in north China. The Cardiovascular Health Score (CHS) was evaluated by the follow-ups of 2006–2007, 2008–2009, 2010–2011 and 2012–2013. The study population (n = 19381) was divided into 5 groups based on the changes in their CHS score between the first two follow-ups (△CHS) of 2006–2007 and 2008–2009 (≤-2, -1, 0, 1, ≥2). The morbidity of hypertension was collected during 2010–2011 and 2012–2013 follow-ups. Data analysis showed that during a median follow-up of 3.79±0.96 years, morbidity of hypertension had a graded relationship with △CHS. As △CHS scored from low to high, the standardized morbidity of hypertension for all participants were 81.40, 75.47, 68.37, 71.43 and 83.13 per 1000 person-year, respectively. An increased △CHS score of 1 was associated with a 10% decrease in the future risk of new-onset hypertension(HR: 0.90, 95% CI: 0.88–0.92). In conclusion, there was a strong inverse relationship between the incidence of new-onset hypertension and elevation of cardiovascular health metrics. Population-wide prevention, especially the promotion of lifestyle improvements, is critical to reducing the morbidity of new-onset hypertension.
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spelling pubmed-49510122016-08-08 Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study Gao, Fei Liu, Xiaoxue Wang, Xizhu Chen, Shouhua Shi, Jihong Zhang, Ying Wu, Shouling Cai, Jun PLoS One Research Article American Heart Association cardiovascular health metrics are intimately related to cardiovascular diseases. Acting as a key independent risk factor for high morbidity and mortality of cardiovascular diseases, hypertension and its relationship between health status get urgent attention. While the influence of individual health status changes and the future risk of new-onset hypertension is rarely understood, the present study applied this construct to assess the changes of cardiovascular health status and the morbidity of hypertension in Kailuan cohort study in north China. The Cardiovascular Health Score (CHS) was evaluated by the follow-ups of 2006–2007, 2008–2009, 2010–2011 and 2012–2013. The study population (n = 19381) was divided into 5 groups based on the changes in their CHS score between the first two follow-ups (△CHS) of 2006–2007 and 2008–2009 (≤-2, -1, 0, 1, ≥2). The morbidity of hypertension was collected during 2010–2011 and 2012–2013 follow-ups. Data analysis showed that during a median follow-up of 3.79±0.96 years, morbidity of hypertension had a graded relationship with △CHS. As △CHS scored from low to high, the standardized morbidity of hypertension for all participants were 81.40, 75.47, 68.37, 71.43 and 83.13 per 1000 person-year, respectively. An increased △CHS score of 1 was associated with a 10% decrease in the future risk of new-onset hypertension(HR: 0.90, 95% CI: 0.88–0.92). In conclusion, there was a strong inverse relationship between the incidence of new-onset hypertension and elevation of cardiovascular health metrics. Population-wide prevention, especially the promotion of lifestyle improvements, is critical to reducing the morbidity of new-onset hypertension. Public Library of Science 2016-07-19 /pmc/articles/PMC4951012/ /pubmed/27434049 http://dx.doi.org/10.1371/journal.pone.0158869 Text en © 2016 Gao et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Gao, Fei
Liu, Xiaoxue
Wang, Xizhu
Chen, Shouhua
Shi, Jihong
Zhang, Ying
Wu, Shouling
Cai, Jun
Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study
title Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study
title_full Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study
title_fullStr Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study
title_full_unstemmed Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study
title_short Changes in Cardiovascular Health Status and the Risk of New-Onset Hypertension in Kailuan Cohort Study
title_sort changes in cardiovascular health status and the risk of new-onset hypertension in kailuan cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951012/
https://www.ncbi.nlm.nih.gov/pubmed/27434049
http://dx.doi.org/10.1371/journal.pone.0158869
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