Effect of Hyperglycemia on Gene Expression during Early Organogenesis in Mice

BACKGROUND: Cardiovascular and neural malformations are common sequels of diabetic pregnancies, but the underlying molecular mechanisms remain unknown. We hypothesized that maternal hyperglycemia would affect the embryos most shortly after the glucose-sensitive time window at embryonic day (ED) 7.5...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Hakvoort, Theodorus B. M., Willemsen, A. Marcel, Jongejan, Aldo, Sokolovic, Milka, Bradley, Edward J., de Boer, Vincent C. J., Baas, Frank, van Kampen, Antoine H. C., Lamers, Wouter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951019/
https://www.ncbi.nlm.nih.gov/pubmed/27433804
http://dx.doi.org/10.1371/journal.pone.0158035

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