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Allosteric Regulation of Fibronectin/α(5)β(1) Interaction by Fibronectin-Binding MSCRAMMs

Adherence of microbes to host tissues is a hallmark of infectious disease and is often mediated by a class of adhesins termed MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Numerous pathogens express MSCRAMMs that specifically bind the heterodimeric human glycoprotein...

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Detalles Bibliográficos
Autores principales: Liang, Xiaowen, Garcia, Brandon L., Visai, Livia, Prabhakaran, Sabitha, Meenan, Nicola A. G., Potts, Jennifer R., Humphries, Martin J., Höök, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951027/
https://www.ncbi.nlm.nih.gov/pubmed/27434228
http://dx.doi.org/10.1371/journal.pone.0159118