Hypomethylation and Genetic Instability in Monosomy Blastocysts May Contribute to Decreased Implantation Potential

DNA methylation is a key epigenetic mechanism responsible for gene regulation, chromatin remodeling, and genome stability, playing a fundamental role during embryonic development. The aim of this study was to determine if these epigenetic marks are associated with chromosomal aneuploidy in human bla...

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Detalles Bibliográficos
Autores principales: McCallie, Blair R., Parks, Jason C., Patton, Alyssa L., Griffin, Darren K., Schoolcraft, William B., Katz-Jaffe, Mandy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951028/
https://www.ncbi.nlm.nih.gov/pubmed/27434648
http://dx.doi.org/10.1371/journal.pone.0159507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951028/
https://www.ncbi.nlm.nih.gov/pubmed/27434648
http://dx.doi.org/10.1371/journal.pone.0159507

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