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Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein
Malaria vaccine development has been hampered by the limited availability of antigens identified through conventional discovery approaches, and improvements are needed to enhance the efficacy of the leading vaccine candidate RTS,S that targets the circumsporozoite protein (CSP) of the infective spor...
Autores principales: | Speake, Cate, Pichugin, Alexander, Sahu, Tejram, Malkov, Vlad, Morrison, Robert, Pei, Ying, Juompan, Laure, Milman, Neta, Zarling, Stasya, Anderson, Charles, Wong-Madden, Sharon, Wendler, Jason, Ishizuka, Andrew, MacMillen, Zachary W., Garcia, Valentino, Kappe, Stefan H. I., Krzych, Urszula, Duffy, Patrick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951032/ https://www.ncbi.nlm.nih.gov/pubmed/27434123 http://dx.doi.org/10.1371/journal.pone.0159449 |
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