Cargando…

Elevation of the Yields of Very Long Chain Polyunsaturated Fatty Acids via Minimal Codon Optimization of Two Key Biosynthetic Enzymes

Eicosapentaenoic acid (EPA, 20:5Δ(5,8,11,14,17)) and Docosahexaenoic acid (DHA, 22:6Δ(4,7,10,13,16,19)) are nutritionally beneficial to human health. Transgenic production of EPA and DHA in oilseed crops by transferring genes originating from lower eukaryotes, such as microalgae and fungi, has been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Fei, Li, Xueying, Li, Xinzheng, Zheng, Desong, Sun, Quanxi, Liu, Jiang, Li, Yaxiao, Hua, Jinping, Qi, Baoxiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951033/ https://www.ncbi.nlm.nih.gov/pubmed/27433934 http://dx.doi.org/10.1371/journal.pone.0158103

Ejemplares similares

Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic Arabidopsis thaliana
por: Yuan, Xiaowei, et al.
Publicado: (2014)

Progress toward Understanding Protein S-acylation: Prospective in Plants
por: Li, Yaxiao, et al.
Publicado: (2017)

Bacterial Long-Chain Polyunsaturated Fatty Acids: Their Biosynthetic Genes, Functions, and Practical Use
por: Yoshida, Kiyohito, et al.
Publicado: (2016)

Algae: Critical Sources of Very Long-Chain Polyunsaturated Fatty Acids
por: Harwood, John L.
Publicado: (2019)

High contents of very long-chain polyunsaturated fatty acids in different moss species
por: Beike, Anna K., et al.
Publicado: (2013)

Very Long Chain Polyunsaturated Fatty Acids Accumulated in Triacylglycerol Are Channeled From Phosphatidylcholine in Thraustochytrium
por: Zhao, Xianming, et al.
Publicado: (2019)

Understanding the Roles of Very-Long-Chain Polyunsaturated Fatty Acids (VLC-PUFAs) in Eye Health
por: Nwagbo, Uzoamaka, et al.
Publicado: (2023)

Novel Approaches for Elongation of Fish Oils into Very-Long-Chain Polyunsaturated Fatty Acids and Their Enzymatic Interesterification into Glycerolipids
por: Honzíková, Tereza, et al.
Publicado: (2023)

Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions
por: Hoernes, Thomas Philipp, et al.
Publicado: (2018)

Putative DHHC-Cysteine-Rich Domain S-Acyltransferase in Plants
por: Yuan, Xiaowei, et al.
Publicado: (2013)

Citramalate synthase yields a biosynthetic pathway for isoleucine and straight- and branched-chain ester formation in ripening apple fruit
por: Sugimoto, Nobuko, et al.
Publicado: (2021)

Effects of parenteral soybean oil lipid emulsion on the long-chain polyunsaturated fatty acid profile in very-low-birth-weight infants
por: Shoji, Hiromichi, et al.
Publicado: (2011)

Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids
por: Xi, Yuecheng, et al.
Publicado: (2021)

Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function
por: Yang, Zhi-Hong, et al.
Publicado: (2023)

Modifying the yeast very long chain fatty acid biosynthetic machinery by the expression of plant 3-ketoacyl CoA synthase isozymes
por: Stenback, Kenna E., et al.
Publicado: (2022)

Biosynthetic Enhancement of the Detection of Bacteria by the Polymerase Chain Reaction
por: Do, Julie S., et al.
Publicado: (2014)

A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics
por: Masschelein, Joleen, et al.
Publicado: (2015)

Stepwise metabolic engineering of docosatrienoic acid – an ω3 very long‐chain polyunsaturated fatty acid with potential health benefits in Brassica carinata
por: Meesapyodsuk, Dauenpen, et al.
Publicado: (2022)

A novel quantification method for retinal pigment epithelium phagocytosis using a very-long-chain polyunsaturated fatty acids-based strategy
por: Gao, Fangyuan, et al.
Publicado: (2023)

Identification and Functional Characterization of Genes Encoding Omega-3 Polyunsaturated Fatty Acid Biosynthetic Activities from Unicellular Microalgae
por: Vaezi, Royah, et al.
Publicado: (2013)

Long-Chain Polyunsaturated Fatty Acids in Inborn Errors of Metabolism
por: Fekete, Katalin, et al.
Publicado: (2010)

Significance of long chain polyunsaturated fatty acids in human health
por: Zárate, Rafael, et al.
Publicado: (2017)

Very Long Chain Marine n-3 Polyunsaturated Fatty Acids in Atherothrombotic Heart Disease. A Brief Review, with a Focus on Metabolic Effects
por: Arnesen, Harald, et al.
Publicado: (2020)

Dietary Betaine Interacts with Very Long Chain n-3 Polyunsaturated Fatty Acids to Influence Fat Metabolism and Circulating Single Carbon Status in the Cat
por: Jewell, Dennis E., et al.
Publicado: (2022)

Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster
por: Böhringer, Nils, et al.
Publicado: (2021)

Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage
por: Wang, Gao-Qian, et al.
Publicado: (2018)

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells
por: Gloster, Tracey M., et al.
Publicado: (2011)

Changes in cholesterol homeostasis modify the response of F1B hamsters to dietary very long chain n-3 and n-6 polyunsaturated fatty acids
por: Lecker, Jaime L, et al.
Publicado: (2011)

Co-expressing Eranthis hyemalis lysophosphatidic acid acyltransferase 2 and elongase improves two very long chain polyunsaturated fatty acid production in Brassica carinata
por: Meesapyodsuk, Dauenpen, et al.
Publicado: (2021)

The association between genetically elevated polyunsaturated fatty acids and risk of cancer
por: Haycock, Philip C., et al.
Publicado: (2023)

Elevated CO(2) has concurrent effects on leaf and grain metabolism but minimal effects on yield in wheat
por: Tcherkez, Guillaume, et al.
Publicado: (2020)

Long Chain Polyunsaturated Fatty Acids (LCPUFAs) in the Prevention of Food Allergy
por: Hoppenbrouwers, Tamara, et al.
Publicado: (2019)

Free Radical Chain Reactions and Polyunsaturated Fatty Acids in Brain Lipids
por: Ng, Sharon C. W., et al.
Publicado: (2022)

Long-Chain Polyunsaturated Fatty Acids and Their Metabolites Regulate Inflammation in Age-Related Macular Degeneration
por: Ren, Jiangbo, et al.
Publicado: (2022)

Minimal interactions at very high transfers
por: Martin, André
Publicado: (1964)

Minimization of Biosynthetic Costs in Adaptive Gene Expression Responses of Yeast to Environmental Changes
por: Vilaprinyo, Ester, et al.
Publicado: (2010)

Exploratory Study of Fatty Acid Profile in Two Filmy Ferns with Contrasting Desiccation Tolerance Reveal the Production of Very Long Chain Polyunsaturated Omega-3 Fatty Acids
por: Rabert, Claudia, et al.
Publicado: (2020)

Determination of very long-chain polyunsaturated fatty acids from 24 to 44 carbons in eye, brain and gonads of wild and cultured gilthead sea bream (Sparus aurata)
por: Serrano, Roque, et al.
Publicado: (2022)

Do universal codon-usage patterns minimize the effects of mutation and translation error?
por: Marquez, Roberto, et al.
Publicado: (2005)

Selection for minimization of translational frameshifting errors as a factor in the evolution of codon usage
por: Huang, Yang, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_v88m6t7t4572c41k2lsl1a32lf